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| Rank | Player | Opp | NFL Fantasy Experts |
|---|---|---|---|
| 1 | Ameer Abdullah RB - LV | @DEN | -- |
| 2 | Josh Adams RB | Bye | -- |
| 3 | Salvon Ahmed RB - MIA | Bye | -- |
| 4 | Cam Akers RB - LA | @NO | -- |
| 5 | Tyler Allgeier RB - ATL | CHI | -- |
| 6 | Darius Anderson RB - HOU | WAS | -- |
| 7 | Alex Armah RB - WAS | @HOU | -- |
| 8 | Ryquell Armstead RB - JAX | Bye | -- |
| 9 | Tyler Badie RB - BAL | CAR | -- |
| 10 | Jake Bargas RB - MIN | DAL | -- |
| 11 | Saquon Barkley RB - NYG | DET | -- |
| 12 | Kenjon Barner RB - TB | Bye | -- |
| 13 | Nick Bawden RB - NYJ | @NE | -- |
| 14 | B.J. Baylor RB - GB | TEN | -- |
| 15 | Nick Bellore RB - SEA | Bye | -- |
| 16 | Eno Benjamin RB - ARI | SF | -- |
| 17 | Giovani Bernard RB - TB | Bye | -- |
| 18 | Khari Blasingame RB - CHI | @ATL | -- |
| 19 | Brandon Bolden RB - LV | @DEN | -- |
| 20 | Reggie Bonnafon RB - WAS | @HOU | -- |
| 21 | Mike Boone RB - DEN | LV | -- |
| 22 | Darius Bradwell RB - CAR | @BAL | -- |
| 23 | Matt Breida RB - NYG | DET | -- |
| 24 | Gary Brightwell RB - NYG | DET | -- |
| 25 | Kennedy Brooks RB - PHI | @IND | -- |
| 26 | Brittain Brown RB - LV | @DEN | -- |
| 27 | Spencer Brown RB - CAR | @BAL | -- |
| 28 | Rex Burkhead RB - HOU | WAS | -- |
| 29 | Michael Burton RB - KC | @LAC | -- |
| 30 | Jason Cabinda RB - DET | @NYG | -- |
| 31 | Raymond Calais RB - LA Q | @NO | -- |
| 32 | Trenton Cannon RB - TEN | @GB | -- |
| 33 | Chris Carson RB - SEA Q | Bye | -- |
| 34 | Cethan Carter RB - MIA | Bye | -- |
| 35 | Michael Carter RB - NYJ | @NE | -- |
| 36 | Ty Chandler RB - MIN | DAL | -- |
| 37 | Nick Chubb RB - CLE | @BUF | -- |
| 38 | Tevin Coleman RB - NYJ | @NE | -- |
| 39 | Alex Collins RB Q | Bye | -- |
| 40 | James Conner RB - ARI | SF | -- |
| 41 | Snoop Conner RB - JAX | Bye | -- |
| 42 | Dalvin Cook RB - MIN | DAL | -- |
| 43 | James Cook RB - BUF | CLE | -- |
| 44 | Nathan Cottrell RB - JAX | Bye | -- |
| 45 | Damarea Crockett RB - DEN | LV | -- |
| 46 | DeeJay Dallas RB - SEA | Bye | -- |
| 47 | Tyrion Davis-Price RB - SF | @ARI | -- |
| 48 | AJ Dillon RB - GB | TEN | -- |
| 49 | Gerrid Doaks RB - MIA | Bye | -- |
| 50 | J.K. Dobbins RB - BAL Q | CAR | -- |
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