| Passing | Rushing | Receiving | Ret | Misc | Fum | Fantasy | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Player | Opp | Yds | TD | Int | Yds | TD | Rec | Yds | TD | TD | FumTD | 2PT | Lost | Points |
| OAK | 5097 | 50 | 12 | 272 | 2 | - | - | - | - | - | 1 | 2 | 417.08 | |
Saquon Barkley RB - NYG IA | DAL | - | - | - | 1307 | 11 | 91 | 721 | 4 | - | - | 1 | - | 385.80 |
| @NO | 50 | 1 | - | 1098 | 7 | 107 | 867 | 6 | - | - | - | 1 | 385.50 | |
Todd Gurley RB - LA IA View News | SF | - | - | - | 1251 | 17 | 59 | 580 | 4 | - | - | 3 | 1 | 372.10 |
| @TB | 4924 | 35 | 7 | 125 | 3 | 1 | 5 | 1 | - | - | 2 | 5 | 354.96 | |
| CAR | - | - | - | 883 | 14 | 81 | 709 | 4 | - | - | 3 | - | 354.20 | |
Ben Roethlisberger QB - PIT IR | CIN | 5129 | 34 | 16 | 98 | 3 | 1 | -1 | - | - | - | 4 | 2 | 341.86 |
| OAK | - | - | - | 151 | 1 | 87 | 1479 | 12 | 1 | - | - | - | 334.00 | |
| JAX | - | - | - | -7 | - | 115 | 1572 | 11 | - | - | - | 2 | 333.50 | |
| JAX | 4165 | 26 | 9 | 551 | 5 | - | - | - | - | - | - | 3 | 331.70 | |
Davante Adams WR - GB O | DET | - | - | - | - | - | 111 | 1386 | 13 | - | - | 1 | - | 329.60 |
| @NYG | - | - | - | 1434 | 6 | 77 | 567 | 3 | - | - | - | 1 | 329.10 | |
Andrew Luck QB | @TEN | 4593 | 39 | 15 | 148 | - | 1 | 4 | - | - | - | 2 | 1 | 327.92 |
| @TB | - | - | - | 12 | - | 113 | 1677 | 8 | - | - | - | 2 | 325.90 | |
| CIN | - | - | - | - | - | 104 | 1297 | 15 | - | - | - | - | 323.70 | |
| CAR | - | - | - | - | - | 125 | 1405 | 9 | - | - | - | 2 | 315.50 | |
Aaron Rodgers QB - GB | DET | 4442 | 25 | 2 | 269 | 2 | - | - | - | - | - | 3 | 3 | 312.58 |
| SF | 4688 | 32 | 12 | 108 | 2 | - | - | - | - | - | 3 | 5 | 310.32 | |
| CHI | - | - | - | 30 | - | 113 | 1373 | 9 | - | - | 1 | 1 | 307.30 | |
Drew Brees QB - NO IA | CAR | 3992 | 32 | 5 | 22 | 4 | 1 | 1 | - | - | - | 1 | 1 | 304.98 |
| ARI | 3448 | 35 | 7 | 376 | - | 1 | -11 | - | - | - | 1 | 2 | 299.42 | |
| CIN | - | - | - | 13 | - | 111 | 1426 | 7 | - | - | 1 | 1 | 296.90 | |
| OAK | - | - | - | - | - | 103 | 1336 | 10 | - | - | - | 1 | 294.60 | |
| ATL | - | - | - | - | - | 86 | 1524 | 8 | - | 1 | - | 1 | 290.40 | |
| @NYG | 3885 | 22 | 8 | 305 | 6 | - | - | - | - | - | 2 | 6 | 285.90 | |